Current Research Interests
Bioinspired materials and biomimetics, biomineralization, nanomechanics, transcritpomics, mechanics of hard and soft biomaterials, structural protein biochemistry, protein engineering applied to materials science, materials characterization by x-ray and vibrational spectroscopy, biofouling and water-resistant adhesives, self-assembly of proteinaceous supramolecular structures.
Ali Miserez is an Associate Professor in the School of Materials Science and Engineering and the School of Biological Sciences at Nanyang Technological University (NTU) in Singapore. He graduated from the Ecole Polytechnique Fédérale de Lausanne (EPFL, Switzerland) with a PhD in Materials Science and Engineering (2003) and a specialization in advanced metal/ceramic composites and mechanics of materials. In 2004, he received a Swiss National Science Foundation post-doc fellowship and moved to the University of California, Santa Barbara (UCSB), where he was affiliated with the Materials Department and the Marine Science Institute. At UCSB, he expanded his research interest towards biological materials and biomimetics working in the group of Prof. Herb Waite. In 2009, he moved to NTU as an Assistant Professor, and in 2011 he was awarded the Singapore National Research Foundation (NRF) Fellowship, a $3 Million individual research grant for early career scientists.
Dr. Miserez’s research is centered on revealing the molecular, physico-chemical, and structural principles from unique biological materials, and on translating these designs into novel biomimetic synthesis strategies. His research group is strongly cross-disciplinary, with molecular biologists, chemists, bio-physicists, and materials scientists combining their expertise towards bioinspired engineering from various angles, including protein biochemistry, extra-cellular tissue transcriptomic, polymer chemistry, biomimetic peptide design, biophysics, and nanomechanics. In recent years, his work has appeared in both general (Science, Nature Materials, Nature Biotechnology, Nature Chemical Biology, Nature Communications) and specialized journals (Biomacromolecules, ACS Nano, Advanced Materials, JBC, Polymer Chemistry, etc, ). He has delivered numerous invited talks, including at various Gordon Research Conferences in the field of bioinspired materials, biomineralization, and biointerfacial science.
The Role of Quasi-Plasticity in the Ultra Contact Damage Tolerance of the Stomatopod Dactyl Club, Nature Materials, vol.14, pp. 943-950, 2015.
Infiltration of Chitin by Protein Coacervates Defines the Squid Beak Mechanical Gradient, Nature Chemical Biology, vol. 11(7), pp. 488–495, 2015. (Cover article).
Multi-Scale Thermal Stability of a Hard Thermoplastic Protein-Based Material, Nature Communications, vol. 6, 8313, 2015
Accelerating the Design of Biomimetic Materials by Integrating RNA-seq with Proteomics and Materials Science, Nature Biotechnology, vol. 31, pp. 908-915, 2013. (Cover article).
The Stomatopod Dactyl Club: A Formidable Damage-Tolerant Biological Hammer, Science, vol. 336, pp. 1275-1280, 2012.