Current Research Interests
There currently exists no standard methodology for tuning surface properties of implantable medical devices. To address this need, we have designed a technology that provides thin coatings that can be readily tuned for specific implant applications using non-toxic, non-solvent, aqueous based green chemistry. The thin coatings are to be applied toward implantable medical devices and biosensors, which is currently limited. The surface modifications that our technology allows will address unmet needs in bioadhesive coatings, blood contacting surfaces, and substrates that promote a living skin-like layer for cloaking of medical implants.
Dr. Terry W.J. Steele currently holds an Assistant Professor position at Materials Science & Engineering-NTU. Currently he focuses energetic engineering students and graduate students into a research dream team, striving to solve today’s most pressing adhesion related ailments. Formerly, Dr. Steele has studied pulmonary drug delivery at the Philipps-Marburg University in Marburg, Germany and earned his PhD in Medicinal Chemistry at the University of Minnesota. His research interests include vascular medical devices, adhesives and biosensors.
Y Zhou, H Chi, YY Wu, RS Marks, TWJ Steele, Organic Solvents Stabilize RNA Aptamer Binding. Accepted July 2016, Talanta
Gao F., Mogal V., O’Rorke R., Djordjevic I., Steele, T.W.J. Elastic Light Tunable Tissue Adhesive Dendrimers Macromol Biosci. 2016 Jul;16(7):1072-82. doi: 10.1002/mabi.201600033
R. D. O’Rorke T. W. J. Steele H. K. Taylor. Bioinspired fibrillar adhesives: a review of analytical models and experimental evidence for adhesion enhancement by surface patterns. J. Adhes.Sci.Tech.30:4, 362-391, DOI:10.1080/01694243.2015.1101183
Ping. J., Gao. F., Chen. J., Webster, R., Steele. T. Adhesive curing through low voltage activation. Aug. 2015, Nature Communications, doi:10.1038/ncomms9050
Ting. C, Ortiz, R. Marks, R Naccached, R Fiorenzo V Steele TWJ Tunable chemical release from polyester thin film by photocatalytic zinc oxide and doped LiYF4 Biomacro. 2015 Jan 12;16(1):364-73.